Sperm from stem cells
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In these tissues, stem cell numbers are controlled simply by the capacity of the niche. Kitadate said, "The lymphatic endothelial cells in the testis were described via the use of electron microscopy in the s, but had scant attention paid to them for a long time. To ensure a balance between the loss of differentiated cells and their replacement in long-lived multicellular organisms, it is critically important to keep the number of tissue stem cells constant. Using genome analysis tools, scientists outlined the multistage process that sperm stem cells undergo during their normal development. Below are relevant articles that may interest you.
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Scientists Create Immature Human Eggs From Stem Cells
In tissues like the testis and ovary of the fruitfly Drosophila and intestine of mammalians, stem cells are clustered in their specialized home where self-renewal-promoting factors are abundant. Failure to maintain stem cell number is thought to underlay the progression of ageing and disease. Simons, Shosei Yoshida. When skeletal muscles, those connected to the bone, are injured, muscle stem cells
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Turning stem cells into sperm
Maher, Cecilia Lindskog, Patrick J. However, sperm stem cells are not clustered in mouse testis, but are highly motile and widely dispersed across the basement membrane. Men with infertility are known to be at higher risk for certain cancers including testicular and prostate cancers. Using genome analysis tools, scientists outlined the multistage process that sperm stem cells undergo during their normal development. National Institutes of Natural Sciences. The results may also have implications for understanding how some cancers arise.
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